To evaluate the respective part of HIV-1, HIV-2 and human T lymphotropic virus (HTLV) infection in Fortaleza, the principal city of the Ceara state (Northeast of Brazil), a cross-sectional seroepidemiological survey was conducted from July 1993 to February 1994 in 6 selected groups : pregnant women, tuberculosis (Tb) patients, sexually transmitted disease (STD) patients, female and male commercial sex workers (CSWs) and prisoners.
Sera were screened by Mixt HIV-1/HIV-2 commercial enzyme immunoassay and ELISA HTLV I/II.
Each serum found positive by ELISA was confirmed by Western blot.
A total of 2917 persons were interviewed, of whom 2754 (94.4%) agreed to participate and gave a blood sample.
Twenty-eight were found to be HIV-1 antibody positive.
The prevalence ranged from 0.25% in pregnant women to 2.9% in male CSWs.
The prevalence was 1% in STD patients and 0.44% in Tb patients.
None of the sera was found positive for HIV-2.
The prevalence of antibodies to HTLV-I varied from 0.12% in pregnant women to 1.21% in female CSWs.
Five sera were positive for HTLV-II.
These results confirm the hypothesis that the HIV epidemic in Northeastern Brazil is still limited to high risk groups.
Repeated cross-sectional surveys of this type should be performed as a surveillance tool to study the dynamics of this epidemic in low prevalence areas.
Defining risk factors should allow targeting of intervention strategies.
Mots-clés Pascal : SIDA, Virose, Infection, Homme, Virus HTLV, Retroviridae, Virus, Virus HIV1, Virus immunodéficience humaine, Lentivirinae, Virus HIV2, Séropositivité, Anticorps, Prévalence, Epidémiologie, Brésil, Amérique du Sud, Amérique, Echelon régional, Milieu urbain, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Human, HTLV virus, Retroviridae, Virus, HIV-1 virus, Human immunodeficiency virus, Lentivirinae, HIV-2 virus, Seropositivity, Antibody, Prevalence, Epidemiology, Brazil, South America, America, Regional scope, Urban environment, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0461568
Code Inist : 002B06D01. Création : 10/04/1997.