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  1. Investigation of a Q-fever outbreak in Northern Italy.

    Article - En anglais

    Objectives 

    A study was conducted to evaluate the extent of a Q-fever epidemic through active case finding in the area of Vicenza (north-eastern Italy), and to identify risk factors for Q-fever in this outbreak.

    Methods 

    1) Descriptive epidemiology ; 2) Seroepidemiological survey ; 3) Case-control study. 1) Epidemic curve and maps with the location of cases.

    Identification of the road followed by the flocks of sheep. 2) Cross-sectional study on humans and flocks of sheep tested for anti-Coxiella burnetii antibodies. 3) Cases were defined by the presence of fever>38 °C plus serological confirmation.

    Controls were 94 apparently healthy individuals attending outpatient facilities for control visits or certification, group-matched by geographical area, age and gender.

    A standardized questionnaire was administered by trained interviewers.

    Odds ratio and 95% confidence intervals (CI) were used to evaluate risk factors for Q-fever.

    Results 

    A total of 58 cases were identified in a 5-month period.

    Male to female ratio was 2.8 : 1 ; mean age was 42 years (range : 20-65 years).

    Twenty-eight patients (48%) were hospitalized

    Fever was accompanied by asthenia (81%), headache (76%), chills (72%), and myalgia and arthralgia (53%) ; cough was present in 47% of patients.

    Rx abnormalities were found in 81% of the patients undergoing chest X-ray.

    Among 111 apparently healthy family members who underwent serological testing, four (3.6%) had antibodies to Coxiella burnetii. (...)

    Mots-clés Pascal : Fièvre Q, Rickettsiose, Rickettsialose, Bactériose, Infection, Foyer infectieux, Homme, Facteur risque, Epidémie, Mouton, Artiodactyla, Ungulata, Mammalia, Vertebrata, Transmission animal homme, Italie, Europe, Transhumance

    Mots-clés Pascal anglais : Q fever, Rickettsial infection, Rickettsialosis, Bacteriosis, Infection, Infectious focus, Human, Risk factor, Epidemic, Sheep, Artiodactyla, Ungulata, Mammalia, Vertebrata, Transmission from animal to man, Italy, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0451853

    Code Inist : 002B05B02L8. Création : 10/04/1997.