We report our experience of 27 orthotopic liver transplantations in 26 patients performed at Queen Mary Hospital, Hong Kong during the period of October 1991 to October 1995.
There were 19 adults and 7 pediatric patients with a mean age of 29 years (range 8 months to 62 years).
The underlying liver diseases of the 26 patients were biliary atresia (n=6), Alagille syndrome (n=1), primary biliary cirrhosis (n=2) cryptogenic cirrhosis (n=2), alcoholic cirrhosis (n=5), Wilson's disease (n=1), fulminant hepatic failure (n=3), polycystic liver (n=2), secondary biliary cirrhosis (n=1), HBV cirrhosis (n=2) and autoimmune hepatitis with hepatocellular carcinoma (n=1).
The pathology leading to re-transplantation in a pediatric patient was post-transplant hepatitis of unknown etiology.
The liver grafts were obtained from 19 brainstem dead and 8 living donors.
The pediatric patient requiring re-transplantation received a left lateral segment graft from her mother.
Two adults received left lobe grafts from their family members.
The overall graft survival is 88% and patient survival is 92%. There were only 2 deaths : one patient developed primary graft nonfunction and died from intracerebral bleeding 39 days after transplantation and the other died from graft rejection resistant to salvage by steroid pulse and OKT3.
The other patients are well with functioning grafts. (...)
Mots-clés Pascal : Transplantation, Foie, Incidence, Don organe, Evolution, Résultat, Homme, Chirurgie, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Transplantation, Liver, Incidence, Organ donation, Evolution, Result, Human, Surgery, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0451661
Code Inist : 002B25G03. Création : 10/04/1997.