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  1. Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) study of admission and management variation in patients hospitalized with respiratory syncytial viral lower respiratory tract infection.

    Article - En anglais


    To describe differences in patients hospitalized with respiratory syncytial virus (RSV) lower respiratory tract infection (LRI) at nine Canadian tertiary care hospitals.

    In addition, this study describes the variation in use of drug and other interventions.


    Data on patients hospitalized with RSV LRI and their outcomes were prospectively collected.

    Demographic data were obtained on enrollment by center study nurses.

    Data recorded daily included clinical assessment, oxygen saturation determination, and interventions (bronchodilators, steroids, ribavirin, antibiotics, intensive care, and mechanical ventilation) received during the day.

    Patients were divided into those with underlying diseases including congenital heart disease, chronic lung disease, immunodeficiency, or multiple congenital anomalies and those who were previously healthy.

    Mean RSV-associated length of stay and the proportion of patients receiving each intervention in each group were determined by hospital.


    A total of 1516 patients were enrolled at nine hospitals during January 1 to June 30,1993, and January 1 to April 30,1994.

    Significant differences were observed among hospitals in the proportion of patients with underlying disease, postnatal age less than 6 weeks, hypoxia, and pulmonary infiltrate on chest radiograph.

    The mean length of stay varied among hospitals from 8.6 to 11.8 days and 4.6 to 6.7 days in compromised and previously healthy patients, respectively. (...)

    Mots-clés Pascal : Bronchiolite, Virose, Infection, Virus syncytial humain, Spumavirinae, Retroviridae, Virus, Voie respiratoire, Traitement, Conduite à tenir, Nourrisson, Homme, Hôpital, Etude comparative, Evaluation, Soin, Canada, Amérique du Nord, Amérique, Appareil respiratoire pathologie, Bronche pathologie

    Mots-clés Pascal anglais : Bronchiolitis, Viral disease, Infection, Human syncytial virus, Spumavirinae, Retroviridae, Virus, Respiratory tract, Treatment, Clinical management, Infant, Human, Hospital, Comparative study, Evaluation, Care, Canada, North America, America, Respiratory disease, Bronchus disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0451519

    Code Inist : 002B05C02C. Création : 10/04/1997.