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  1. Difficulty in elucidating the male role in cervical cancer in Colombia, a high-risk area for the disease.

    Article - En anglais


    Epidemiologic evidence has been inconclusive in linking men's sexual behavior and genital human papillomaviruses (HPVs) with cervical cancer risk in their sexual partners in areas with a high incidence of cervical cancer.


    This study assesses the role of men's sexual behavior and the presence of penile HPV DNA on the risk of their wives'developing cervical neoplasia in an area in Colombia with a high incidence of cervical cancer.


    A total of 210 husbands of women with cervical intraepithelial neoplasia grade III (n=118) or invasive squamous cell carcinoma of the cervix (n=92) and a total of 262 husbands of women recruited as control subjects (173 and 89, respectively) were interviewed.

    Questionnaires included detailed information on sexual behavior.

    Exfoliated cells were obtained from the glans penis and from the distal urethra of the penis.

    The specimens were analyzed for HPV DNA by use of a polymerase chain reaction-based assay that included a generic probe and 25 type-specific probes.

    Serum specimens were collected and analyzed for antibodies to Chlamydia trachomatis, Treponema pallidum, herpes simplex virus type II, and Neisseria gonorrhoeae.


    Limited education (adjusted odds ratio [OR]=4.4 ; 95% confidence interval [CI]=1.9-9.8 ; for no schooling versus secondary or higher education) and presence of antibodies to C. trachomatis.

    (adjusted OR=2.5 ; 95% CI=1.5-4. (...)

    Mots-clés Pascal : Tumeur maligne, Col utérus, Facteur risque, Epidémiologie, Comportement sexuel, Conjoint, Mâle, Papillomavirus humain, Papillomavirus, Papovaviridae, Virus, DNA, Colombie, Amérique du Sud, Amérique, Homme, Appareil génital femelle pathologie, Col utérus pathologie

    Mots-clés Pascal anglais : Malignant tumor, Uterine cervix, Risk factor, Epidemiology, Sexual behavior, Spouse, Male, Human papillomavirus, Papillomavirus, Papovaviridae, Virus, DNA, Colombia, South America, America, Human, Female genital diseases, Uterine cervix diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0449742

    Code Inist : 002B20C02. Création : 10/04/1997.