Testicular nonseminoma and seminoma in relation to perinatal characteristics.
Testicular cancer incidence peaks during the third decade of life, and an increasing trend in the occurrence of this disease has been seen in many countries.
Few risk factors have been established for testicular cancer, but evidence suggests that causal factors operate early in life, perhaps even in utero.
We performed a case-control study to evaluate specific perinatal characteristics as risk factors for the two main histopathologic types of testicular cancer : seminomas and nonseminomas.
Two hundred thirty-two case patients with invasive testicular cancer and 904 individually matched control subjects (all singleton births), nested in a cohort of men born at 10 hospitals in Sweden from 1920 through 1978, were included in the study.
Perinatal information about the study subjects and their parents was obtained from birth records.
For the mothers, information was recorded concerning age at menarche, marital status, parity, age at delivery, maternal weight at delivery and at first visit to a maternal-care center, education and/or profession, and any medical problems encountered during pregnancy or after delivery.
For the fathers, information was obtained concerning age at delivery and education and/or profession. (...)
Mots-clés Pascal : Séminome, Testicule, Tumeur non séminomateuse, Facteur risque, Périnatal, Ictère, Poids naissance, Statut socioéconomique, Epidémiologie, Suède, Europe, Homme, Appareil génital mâle pathologie, Testicule pathologie, Tumeur maligne, Etude cas témoin
Mots-clés Pascal anglais : Seminoma, Testicle, Non seminomatous tumor, Risk factor, Perinatal, Jaundice, Birth weight, Socioeconomic status, Epidemiology, Sweden, Europe, Human, Male genital diseases, Testicular diseases, Malignant tumor, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0447652
Code Inist : 002B20B02. Création : 10/04/1997.