Objectives The purpose of this study was to search for evidence of an association between occupational arsenic exposure and diabetes mellitus, as implied by the relation of this disease to arsenic in drinking water in a recent study from Taiwan.
Methods A case-referent analysis on death records of 5498 individuals in the art glass producing part of southeastern Sweden was performed.
Out of all the enrolled subjects, 888 were glass workers.
According to occupational title, glassblowers, foundry workers, and unspecified workers were regarded as potentially exposed to arsenic.
Persons with a diagnosis of diabetes mellitus either as an underlying or contributing cause of death were considered cases.
Referents were decedents without any indication of cancer, cardiovascular disease, or diabetes.
Results A slightly elevated risk [Mantel-Haenszel odds ratio (MH-OR) 1.2,95% confidence interval (95% CI) 0.82-1.8] was found for diabetes mellitus among the glassworks employees, especially in combination with cardiovascular disease (MH-OR 1.4,95% CI 0.81-2.3).
For the glassblowers, other foundry workers and unspecified glassworkers probably exposed to arsenic, the M-H odds ratio was 1.4 (95% CI 0.92-2.2).
Unspecified glass workers, who probably included persons with high exposure, carried the higher risk (MH-OR 1.8,95% CI 1.1-2.8). (...)
Mots-clés Pascal : Diabète, Arsenic, Exposition professionnelle, Industrie verre, Médecine travail, Epidémiologie, Facteur risque, Toxicité, Homme, Suède, Europe, Endocrinopathie, Métal
Mots-clés Pascal anglais : Diabetes mellitus, Arsenic, Occupational exposure, Glass industry, Occupational medicine, Epidemiology, Risk factor, Toxicity, Human, Sweden, Europe, Endocrinopathy, Metal
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0438029
Code Inist : 002B03L05. Création : 10/04/1997.