Large amounts of the powerful pesticide sodium pentachlorophenol (Na-PCP) salt have been sprayed over vast areas in central China to control schistosomiasis, a parasitic disease of epidemic proportions.
Approximately 6000 tons of Na-POP are produced in China annually.
Dioxins, a class of toxic, persistent compounds, are found as impurities in commercial Na-PCP products.
These contaminants are released into the environment and significantly contribute to human exposure to dioxins in China.
This study was carried out to determine dioxin levels in environmental and human tissue samples from one schistosomiasis area to evaluate the health risks associated with exposure to Na-PCP.
Na-PCP pesticide was applied in 1972,1973, and again in 1978.
A total of approximately 454 tons and 902 tons of 5 ppm Na-PCP in water were sprayed over large land and lake problem schistosomiasis areas, respectively.
The groups studied were (1) sprayers or handlers of Na-PCP, (2) persons living in the sprayed areas, and (3) persons living in unsprayed areas 300 km north of the sprayed lake located in a city in the Jiangxi province.
Individual whole-blood and breast-milk samples were collected and later pooled for dioxin analysis.
Also, a sample of commercial Na-PCP was collected.
In addition, sediment samples from the lake where Na-PCP was sprayed were collected from four different sites and one control sample was collected from a non-schistosomiasis area. (...)
Mots-clés Pascal : Pesticide, Biocide, Dibenzo-p-dioxine(2,3,7,8-tétrachloro), Dibenzofurane(polychloro), Dibenzo-p-dioxine(polychloro), Exposition professionnelle, Médecine travail, Homme, Chine, Asie, Sexe, Epidémiologie, Impureté, Molluscicide, Schistosomiase, Trématodose, Helminthiase, Parasitose, Infection, Taux, Milieu biologique, Tissu, Phénols, Phénol(perchloro)
Mots-clés Pascal anglais : Pesticides, Biocide, Occupational exposure, Occupational medicine, Human, China, Asia, Sex, Epidemiology, Impurity, Molluscicide, Schistosomiasis, Trematode disease, Helminthiasis, Parasitosis, Infection, Rate, Biological medium, Tissue, Phenols, Pentachlorophenol
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0437154
Code Inist : 002B03G. Création : 10/04/1997.