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  1. Early sensitization to farming-related antigens among young farmers : Analysis of risk factors.

    Article - En anglais

    It was the aim of this study to investigate the prevalence of and risk factors for IgE-and IgG-mediated allergy in young farmers.

    We investigated 147 young men attending a farming college in the Austrian Tyrol and 57 age-matched pupils at a grammar school.

    All individuals completed a questionnaire and had spirometry, skin prick tests, total and specific IgE analysis, and testing for precipitins against thermophilic actinomycetes and true fungi.

    In the farming group, a family history of atopy or asthma was reported less frequently than in the control group (p<0.001) but there were no differences in the frequencies of actual respiratory symptoms.

    Forced expiratory volume in the first second (FEV1) was slightly lower in the farmers than in the pupils (p<0.05).

    There was no difference in the prevalence of IgE-mediated allergy.

    Nine of the farmers but none of the pupils had precipitating antibodies against Faeni rectivirgula (p<0.05).

    Overall reactivity (as defined by at least one positive finding with the skin prick test, specific IgE, or precipitins) was associated with larger farming estates, lack of a hay-drying device, use of mouldy hay, and positive family history of asthma (p<0.05).

    We conclude that in farmers, precipitin formation may occur at an early age and that even in younger age groups there is a clear relationship between allergic sensitization and occupational allergen exposure.

    Mots-clés Pascal : Agriculteur, Adolescent, Homme, Facteur risque, Atopie, Sensibilisation, Antigène, Prévalence, Allergie, Asthme, Immunopathologie, Appareil respiratoire pathologie, Bronchopneumopathie obstructive

    Mots-clés Pascal anglais : Farmer, Adolescent, Human, Risk factor, Atopy, Sensitization, Antigen, Prevalence, Allergy, Asthma, Immunopathology, Respiratory disease, Obstructive pulmonary disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0431898

    Code Inist : 002B06C01. Création : 10/04/1997.