Association between use of spermicide-coated condoms and Escherichia coli urinary tract infection in young women.
Diaphragm/spermicide use increases the risk of urinary tract infection (UTI).
To determine whether spermicide-coated condoms are also associated with an increased risk of UTI, the authors conducted a case-control study at a large health maintenance organization in Seattle, Washington.
Cases were sexually active young women with acute UTI caused by Escherichia coli, identified from computerized laboratory files during 1990-1993.
Age-matched controls were randomly selected from the enrollment files of the plan.
Of 1,904 eligible women, 604 cases and 629 controls (65%) were interviewed.
During the previous year, 40% of the cases and 31% of the controls had been exposed to any type of condom.
The unadjusted odds ratio for UTI increased with frequency of condom exposure from 0.91 (95% confidence interval (Cl) 0.65-1.28) for weekly or less during the previous month to 2.11 (95% Cl 1.37-3.26) for more than once weekly.
Exposure to spermicide-coated condoms conferred a higher risk of UTI, with odds ratios ranging from 1.09 (95% Cl 0.58-2.05) for use weekly or less to 3.05 (95% Cl 1.47-6.35) for use more than once weekly.
In multivariate analyses, intercourse frequency (odds ratio (OR)=1.14 per weekly episode), history of UTI (OR=2.64), and frequency of spermicide-coated condom exposure (OR=3.34 for more than once weekly and 5.65 for use more than twice weekly) were independent predictors of UTI. (...)
Mots-clés Pascal : Contraceptif, Voie locale, Condom, Diaphragme(contraception), Spermicide, Complication, Epidémiologie, Infection, Voie urinaire, Femme, Homme, Adulte jeune, Escherichia coli, Enterobacteriaceae, Bactérie, Etats Unis, Amérique du Nord, Amérique
Mots-clés Pascal anglais : Contraceptive, Local administration, Condom, Diaphragm pessary, Spermicide, Complication, Epidemiology, Infection, Urinary tract, Woman, Human, Young adult, Escherichia coli, Enterobacteriaceae, Bacteria, United States, North America, America
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0419998
Code Inist : 002B20A02. Création : 10/04/1997.