Association between low plasma vitamin E concentration and progression of early cortical lens opacities.
The authors evaluated the association between plasma vitamin E content and progression of eye lens opacities.
A total of 410 hypercholesterolemic eastern Finnish men participated in the study from January 1990 to September 1993 in Kuopio, Finland.
Lens opacities were classified three times at 18-month intervals using the Lens Opacities Classification System II.
A low plasma vitamin E level (lowest quartile) was associated with a 3.7-fold excess risk (95% confidence interval 1.2-11.8) of the progression of early cortical lens opacities compared with the highest quartile (p=0.028).
In addition, the number of cigarettes smoked daily was a significant predictor of the progression of cortical lens opacity (relative risk=1.06 per cigarette, 95% confidence interval 1.003-1.12).
The progression of nuclear lens opacities was not associated with either the plasma vitamin E content or smoking.
The data suggest that low plasma vitamin E content may be associated with increased risk of the progression of early cortical lens opacity.
Mots-clés Pascal : Cataracte, Epidémiologie, Homme, Antioxydant, alpha-Tocophérol, Vitamine, Finlande, Europe, Oeil pathologie, Cristallin pathologie, Segment antérieur pathologie
Mots-clés Pascal anglais : Cataract, Epidemiology, Human, Antioxidant, alpha-Tocopherol, Vitamin, Finland, Europe, Eye disease, Lens disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0419235
Code Inist : 002B09G. Création : 10/04/1997.