This population-based case-control study examined the association between selected nutrients, foods, and diet behaviors and bladder cancer.
Bladder cancer cases (n=262) were identified from the Surveillance, Epidemiology, and End Results Program cancer registry for western Washington, and controls (n=405) were identified through random digit dialing.
Cases were diagnosed between January 1987 and June 1990, and eligible subjects were Caucasian, aged 45-65 years, and residents of King, Pierce, or Snohomish counties.
Subjects completed a self-administered, 71-item food frequency questionnaire and a structured telephone interview.
Analyses were conducted by logistic regression analysis and included adjustment for age, sex, smoking (current, former, never), and county.
Odds ratios and their 95% confidence intervals for highest versus lowest level of intake were examined.
An inverse association was found between the risk of bladder cancer and dietary retinol (odds ratio (OR) across quartiles : 1.00,1.09,0.97, and 0.52 ; 95% CI 0.29-0.97 ; trend p value=0.03) and dietary vitamin C (OR across quartiles : 1.00,0.96,0.67, and 0.50 ; 95% CI 0.28-0.88 ; trend p value=0.009), adjusted for calories.
The use of multivitamin supplements daily over the 10-year period ending 2 years before diagnosis versus no use was associated with a decreased risk of bladder cancer (OR=0.39 ; 95% Cl 0.24-0.63) as was use of supplemental vitamin C (OR for>502 mg/day over the 10 years vs. none=0. (...)
Mots-clés Pascal : Tumeur maligne, Vessie urinaire, Epidémiologie, Homme, Régime alimentaire, Comportement alimentaire, Consommation alimentaire, Vitamine, Fruit, Légume, Nutriment, Etats Unis, Amérique du Nord, Amérique, Appareil urinaire pathologie, Voie urinaire pathologie, Vessie pathologie
Mots-clés Pascal anglais : Malignant tumor, Urinary bladder, Epidemiology, Human, Diet, Feeding behavior, Food intake, Vitamin, Fruit, Vegetable, Nutrient, United States, North America, America, Urinary system disease, Urinary tract disease, Bladder disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0418362
Code Inist : 002B14D02. Création : 10/04/1997.