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  1. Legionellosis in a bone marrow transplant center.

    Article - En anglais

    We reviewed 10 cases of culture proven legionellosis that occurred at a marrow transplant center (Fred Hutchinson Cancer Research Center, Seattle, WA, USA) over a 6-year period ending in 1993.

    Infections were caused by four species of Legionella with no apparent clustering of cases.

    Detection of Legionella using direct fluorescent antibody assays proved unreliable due to the high proportion of rare Legionella species isolated.

    The clinical presentation, course and outcome of patients varied and did not correlate with underlying disease, type of transplant, transplant day or engraftment status.

    However, five of the seven patients infected with non-pneumophila species recovered from their pneumonia compared to none of the three patients infected with L. pneumophila.

    Persistent or relapsed infection after 3 weeks of appropriate therapy was documented in one case suggesting that prolonged antibiotic treatment is indicated in these patients.

    Mots-clés Pascal : Greffe, Moelle osseuse, Homme, Service santé, Milieu hospitalier, Epidémiologie, Complication, Légionellose, Bactériose, Infection, Washington, Etats Unis, Amérique du Nord, Amérique, Transfusion

    Mots-clés Pascal anglais : Graft, Bone marrow, Human, Health service, Hospital environment, Epidemiology, Complication, Legionellosis, Bacteriosis, Infection, Washington, United States, North America, America, Transfusion

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0417202

    Code Inist : 002B27D02. Création : 10/04/1997.