Epidemiology of childhood leukemia in Hokkaido, Japan.
The population-based epidemiological indices (crude incidence, survival rate, mortality, etc.) of childhood leukemia (0-14 years of age) from 1969 to 1993 in Hokkaido Prefecture, Japan, were calculated, using data obtained from the Registry of Childhood Malignancies in Hokkaido Prefecture.
A total of 1,084 cases of leukemia were diagnosed in the 1969-93 period.
The annual incidence of all types of leukemia from 1984 to 1993 was about 4 per 100,000 children aged 0-14 years, with the incidence of ANLL decreasing slightly and that of ALL increasing.
The ratio of ALL/ANLL could similarly be seen to be increasing in all age groups.
Out of a cohort of 100,000 live births, about 65 children developed leukemia by 14 years of age, and in this longitudinal observation the ratio of ALL/ANLL was increasing.
The incidence of ALL and ANLL and the ratio of ALL/ANLL in Japanese children are approaching those of Caucasians.
Approximately 80% of the ALL cases were of the LI type (FAB classification), and about 65% of these could be immunologically classified as « common » ALL.
The 5-year survival rate of T-and B-cell ALL cases was 50% or less, while that of « common » ALL cases was about 80%.
Mots-clés Pascal : Leucémie, Enfant, Homme, Epidémiologie, Hokkaïdo, Japon, Asie, Registre, Hémopathie maligne
Mots-clés Pascal anglais : Leukemia, Child, Human, Epidemiology, Hokkaido, Japan, Asia, Register, Malignant hemopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0416998
Code Inist : 002B19B. Création : 10/04/1997.