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  1. Epidemiology of childhood leukemia in Hokkaido, Japan.

    Article - En anglais

    The population-based epidemiological indices (crude incidence, survival rate, mortality, etc.) of childhood leukemia (0-14 years of age) from 1969 to 1993 in Hokkaido Prefecture, Japan, were calculated, using data obtained from the Registry of Childhood Malignancies in Hokkaido Prefecture.

    A total of 1,084 cases of leukemia were diagnosed in the 1969-93 period.

    The annual incidence of all types of leukemia from 1984 to 1993 was about 4 per 100,000 children aged 0-14 years, with the incidence of ANLL decreasing slightly and that of ALL increasing.

    The ratio of ALL/ANLL could similarly be seen to be increasing in all age groups.

    Out of a cohort of 100,000 live births, about 65 children developed leukemia by 14 years of age, and in this longitudinal observation the ratio of ALL/ANLL was increasing.

    The incidence of ALL and ANLL and the ratio of ALL/ANLL in Japanese children are approaching those of Caucasians.

    Approximately 80% of the ALL cases were of the LI type (FAB classification), and about 65% of these could be immunologically classified as « common » ALL.

    The 5-year survival rate of T-and B-cell ALL cases was 50% or less, while that of « common » ALL cases was about 80%.

    Mots-clés Pascal : Leucémie, Enfant, Homme, Epidémiologie, Hokkaïdo, Japon, Asie, Registre, Hémopathie maligne

    Mots-clés Pascal anglais : Leukemia, Child, Human, Epidemiology, Hokkaido, Japan, Asia, Register, Malignant hemopathy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0416998

    Code Inist : 002B19B. Création : 10/04/1997.