A case-control interview study was used to evaluate the relationship between breast cancer risk and residential proximity to industrial facilities and traffic for pre-and postmenopausal women in Nassau and Suffolk Counties on Long Island, New York.
A geographic information system was used to assign industry and traffic counts to 1-km2 grid cells (5-km2 grid cells for traffic) and to assign potential exposure values to study subjects, based on 20-y residential histories.
A significantly elevated risk of breast cancer was observed among postmenopausal subjects who were ever potentially exposed to chemical facilities (Nassau County adjusted odds ratio [OR]=1.61,95% confidence interval [95% Cl]=1.06-2.43 ; Suffolk County adjusted OR=1.58,95% CI=0.71-3.51.
This elevated risk, however, was not observed among premenopausal subjects.
Risk increased for postmenopausal subjects as number of chemical facilities increased from one (adjusted OR=1.45,95% CI=0.93-2.25) to two or more (adjusted OR=3.47,95% CI=1.06-11.38).
Crude and adjusted ORs for high traffic density were elevated among Nassau-but not Suffolk-county subjects and were not significant statistically.
Mots-clés Pascal : New York, Etats Unis, Amérique du Nord, Amérique, Milieu urbain, Epidémiologie, Tumeur maligne, Glande mammaire, Homme, Zone industrielle, Pollution, Trafic routier urbain, Femme, Préménopause, Postménopause, Variation géographique, Glande mammaire pathologie, Etude cas témoin
Mots-clés Pascal anglais : New York, United States, North America, America, Urban environment, Epidemiology, Malignant tumor, Mammary gland, Human, Industrial area, Pollution, Urban road traffic, Woman, Premenopause, Postmenopause, Geographical variation, Mammary gland diseases, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0416983
Code Inist : 002B20E02. Création : 10/04/1997.