Malignant melanoma of the conjunctiva : occurrence and survival following surgery and radiotherapy in a Danish population.
- Purpose :
To describe patient characteristics, risk of recurrence, and survival in patients with premalignant and malignant melanocytic lesions of the conjunctiva.
Methods : In a retrospective study, 55 cases with a minimum follow-up of 10 years were reviewed.
Results : The actuarial 5-and 10-year survival rates were 86% (95% Cl : 76-96%) and 73% (95% Cl : 60-87%) respectively.
The 5-year risk of local recurrence was 35% (95% Cl : 21-49%), and the 10-year risk was 43% (95% Cl : 28-58%). Primary acquired melanosis with atypia was the first manifestation in 13 cases, malignant melanoma in 42 cases.
No significant difference in survival and recurrence was found between the two groups or by gender, location of primary lesion, histological characteristics, or extent of surgical procedure.
A minimum incidence of 0.052 cases a year per 100000 in Denmark was calculated. - Conclusion : The results are estimated to represent a nationwide sample of patients.
No prognostic factors of significance were identified.
Mots-clés Pascal : Mélanome malin, Conjonctive, Exérèse, Radiothérapie, Traitement associé, Incidence, Survie, Postopératoire, Epidémiologie, Danois, Enfant, Homme, Tumeur maligne, Oeil pathologie, Conjonctive pathologie, Chirurgie, Traitement instrumental
Mots-clés Pascal anglais : Malignant melanoma, Conjunctiva, Exeresis, Radiotherapy, Combined treatment, Incidence, Survival, Postoperative, Epidemiology, Danish, Child, Human, Malignant tumor, Eye disease, Conjunctiva disease, Surgery, Instrumentation therapy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0415561
Code Inist : 002B09B. Création : 10/04/1997.