A comparison of cardiovascular risk as measured by compound blood lipid indices and two indices including lifestyle factors in occupational health service.
Healthy employees in a non-manufacturing firm (n=252) were divided into low and high cardiovascular risk subjects in order to compare different indices of cardiovascular risk for use in occupational health service.
The levels of total cholesterol (TC), a compound index of blood lipid components, the'atherogenic index' (ATH-index) defined as ([TC-HDLc] x [apoB])/ ([HDLc] x [apoA]), and two other compound indices, one Norwegian (Westlund) and one Scottish (Dundee score) were compared.
Information on smoking habits and blood pressure were part of the two last indices.
Cut-off values to separate between low and high risk subjects were defined with TC=6.5mmol/l, HDLc=0.9mmol/l, apoA=1.8g/l and apoB=1.3g/l, all values based on clinical guidelines in Norway.
No smoking and a systolic blood pressure
According to the three indices (ATH, Westund and Dundee) 102,25 and 116 employees were allocated to the increased risk group.
Persons allocated to the increased risk group by the combined indices and not by the compound index were practically all smokers.
Systolic blood pressure differed between indices only for persons with extreme pressures.
A compound blood lipid index of CV risk, which may be drawn easily in an occupational health setting in an unfasting state and sent by post to a laboratory, mimics the allocation of persons to an increased risk group using combined indices. (...)
Mots-clés Pascal : Indicateur, Etude comparative, Cholestérol, Lipide, Facteur risque, Appareil circulatoire, Homme, Lipoprotéine HDL, Apolipoprotéine, Mode de vie, Médecine travail
Mots-clés Pascal anglais : Indicator, Comparative study, Cholesterol, Lipids, Risk factor, Circulatory system, Human, Lipoprotein HDL, Apolipoproteins, Life habit, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0414399
Code Inist : 002B30B04. Création : 10/04/1997.