A case-control study in Somerset and east Devon was undertaken to investigate possible risk factors for prostatic cancer.
A total of 159 cases, diagnosed at Taunton, Yeovil and Exeter hospitals between May 1989 and May 1991, were identified prospectively and interviewed with a structured questionnaire.
A total of 161 men diagnosed with benign prostatic hypertrophy and 164 non-urological hospital controls were given identical questionnaires.
The questionnaire covered a wide range of factors identified from previous studies, but the central hypotheses for this study related to diet (fat and green vegetables), sexual activity and farming as an occupation.
This study found no association between farming and risk of prostatic cancer (odds ratio=0.74,95% confidence interval 0.46-1.18), nor with sexual activity as measured by number of sexual partners (chi-squared test for trend P=0.52).
A history of sexually transmitted disease was not significantly associated with prostatic cancer, but the numbers involved were very small and the odds ratio of 2.06 (0.38-11.2) is consistent with the hypothesis.
A range of questions aimed at eliciting dietary fat intake produced no significant associations, although meat consumption showed increasing risk with increasing consumption (test for trend P=0.005).
Increased consumption of leafy green vegetables was associated with lower risk, but not significantly so (test for trend P=0.16). (...)
Mots-clés Pascal : Tumeur maligne, Prostate, Facteur risque, Epidémiologie, Facteur sexuel, Relation sexuelle, Exploitation agricole, Exposition professionnelle, Substance toxique, Régime alimentaire, Royaume Uni, Europe, Homme, Appareil génital mâle pathologie, Appareil urinaire pathologie, Prostate pathologie, Médecine travail, Etude cas témoin
Mots-clés Pascal anglais : Malignant tumor, Prostate, Risk factor, Epidemiology, Sexual factor, Sexual intercourse, Farming, Occupational exposure, Toxic materials, Diet, United Kingdom, Europe, Human, Male genital diseases, Urinary system disease, Prostate disease, Occupational medicine, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0409313
Code Inist : 002B14D02. Création : 10/04/1997.