Parkinson's disease (PD) shows a geographical variation.
All prescriptions for anti-parkinsonian drugs were recorded for a half-year in a region with low L-dopa consumption.
Hospital and outpatient records were studied and physicians were asked to supply details of PD patients in the region, with 147,777 inhabitants.
The crude prevalence was 115 PD per 100,000 inhabitants, based on 170 cases.
In contrast to other studies we report an age-standardized prevalence, which was 76 per 100,000, using the European Standard Population as reference.
The corresponding approximate incidences were 11.0 (crude) and 7.9 (age-standardized) per 100,000 person-years.
Male preponderance appeared in all age groups.
Mean age at onset was 65.6 years, the highest figure reported.
Variation between studies for age at onset, differences in prevalence, and male preponderance suggest environmental risk factors to be of importance for PD.
Mots-clés Pascal : Parkinson maladie, Epidémiologie, Homme, Age, Sexe, Prévalence, Incidence, Suède, Europe, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Extrapyramidal syndrome, Maladie dégénérative
Mots-clés Pascal anglais : Parkinson disease, Epidemiology, Human, Age, Sex, Prevalence, Incidence, Sweden, Europe, Nervous system diseases, Central nervous system disease, Cerebral disorder, Extrapyramidal syndrome, Degenerative disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0407426
Code Inist : 002B17G. Création : 10/04/1997.