The aim of this study was to obtain a conservative estimate of the current incidence of low serum cobalamin levels (cobalaminopenia) in a modern, postindustrial region in Sweden.
All serum cobalamin determinations made during 1993 in one health care area (Umea) with 131,393 inhabitants were analyzed.
These analyses were all performed in a single laboratory ; data were available for 6451 serum samples from 5225 patients.
Serum cobalamin levels<145 pmol/L (corresponding to the lowest decile determined in previous years) were identified in 582 samples from 473 patients.
Data from these samples were further investigated to determine distributions of cobalaminopenia based on age and sex.
The overall minimal incidence of low serum cobalamin levels (<145 pmol/L) was 0.36% ; the incidence increased with age.
Low serum cobalamin levels occurred significantly more frequently in women aged 15 to 44 years than in men in the same age group.
In contrast, men older than 70 years of age were more prone to cobalaminopenia than women of the same age.
The current minimal incidence of low serum cobalamin values suggests adequate functioning of social and health care networks, with an overall minimal incidence of cobalaminopenia of 0.36% and a projected incidence of cobalaminopenia in the Umea health care area of approximately 1%.
Mots-clés Pascal : Cobalamine, Sérum, Homme, Normal, Suède, Europe, Déficit, Incidence, Distribution, Sexe, Age, Epidémiologie, Cyanocobalamine
Mots-clés Pascal anglais : Cobalamine, Serum, Human, Normal, Sweden, Europe, Deficiency, Incidence, Distribution, Sex, Age, Epidemiology, Cyanocobalamin
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0406143
Code Inist : 002B30A01A2. Création : 10/04/1997.