We examined the hypothesis that low plasma cholesterol concentration was associated with minor psychiatric disturbance in a cross-sectional study of 410 male and 138 female civil servants.
Psychiatric disturbance was measured using the 30-item General Health Questionnaire (GHQ).
Mean GHQ score did not vary significantly with quartile of total cholesterol concentration.
After adjustment for confounding variables a significant trend of increasing mean GHQ with increasing cholesterol concentration emerged.
In a logistic regression analysis subjects in the highest quartile of cholesterol concentration had an adjusted odds ratio for being a « psychiatric case » of 2.0 (95% confidence interval, 1.1-2.5) compared with those in the lowest quartile.
This relationship reversed when using a higher cutoff point to define more severe cases, although the trend was not statistically significant.
Mots-clés Pascal : Trouble psychiatrique, Epidémiologie, Homme, Taux, Cholestérol, Etude transversale, Cholestérolémie, Lipide
Mots-clés Pascal anglais : Mental disorder, Epidemiology, Human, Rate, Cholesterol, Cross sectional study, Cholesterolemia, Lipids
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0405646
Code Inist : 002B18C14. Création : 10/04/1997.