The objective of the present study was to determine whether paternal and maternal history of hypertension contributes to the probability of an individual having hypertension before and after other measured traits, including sex, are considered.
A cross-sectional sample of 217 men and 196 women was selected from the general Caucasion population of Rochester, Minnesota without respect to the hypertension status of subjects and their parents.
Logistic regression analyses indicated that when no other information was considered, paternal history of hypertension contributed to the probability of having hypertension in men (khi2=4.14, df=1, p=0.042) and in women (khi2=4.12, df=1, p=0.042).
The odds ratio associated with paternal history of hypertension was 2.80 in men (95% confidence interval [CI]=1.0-8.0) ; the odds ratio was 4.11 in women (95% CI=0.9-19.3).
Maternal history of hypertension provided a marginally significant contribution to the prediction of probability of having hypertension in men (khi2=3.86, df=1, p=0.049 in men), and less so in women (khi2=3.31, df=1, p=0.068).
The odds ratios associated with maternal history of hypertension were 2.85 in men (95% CI=0.9-8.8) and 3.60 in women (95% CI=0.8-16.9).
A stepwise selection algorithm was used to select other predictors of hypertension in men and women.
Other predictors of hypertension identified in men were age and sodium-lithium countertransport level. (...)
Mots-clés Pascal : Hypertension artérielle, Homme, Epidémiologie, Sexe, Prédisposition, Histoire familiale, Régression logistique, Déterminisme génétique, Minnesota, Etats Unis, Amérique du Nord, Amérique, Appareil circulatoire pathologie
Mots-clés Pascal anglais : Hypertension, Human, Epidemiology, Sex, Predisposition, Family story, Logistic regression, Genetic inheritance, Minnesota, United States, North America, America, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0400501
Code Inist : 002B12B05B. Création : 10/04/1997.