Mortality among workers exposed to carbon disulfide.
Mortality experience was investigated at a plant in Ontario that produced viscose rayon, with carbon disulfide as a main raw material.
Work-history records for 279 deceased workers at the plant (plant A) were obtained and compared with those for 511 deceased workers at a pulp and paper plant in the same city (plant B).
In a proportional mortality analysis, using as a reference the general population of Ontario, at both plants there were fewer deaths from ischemic heart disease than expected (the proportional mortality ratios [PMRs] were 83 at plant A and 95 at plant B) but more deaths than expected from cerebrovascular disease (PMRs were 115 at plant A and 149 at plant B).
In a subgroup of plant A workers who had been employed in high-carbon-disulfide exposure areas, deaths from ischemic heart disease were less than expected (PMR=82), particularly among those who worked in these areas for more than 5 y. Most deaths occurred among those aged 65 y or more.
Mortality from strokes, however, was greater than expected (PMR=207, p<. 05) ; the excess was confined to workers who died at age 65 y or older (PMR=229, p=01).
Proportional mortality from strokes was also increased in the pulp workers among those who died at age 65 y or older (PMR=153).
In a case-control analysis, the risk of ischemic heart disease at plant A was slightly less than at plant B (odds ratio [OR]=0.92,95% confidence interval [CI]=0.60-1. (...)
Mots-clés Pascal : Carbone disulfure, Toxicité, Mortalité, Accident cérébrovasculaire, Exposition professionnelle, Médecine travail, Industrie textile, Homme, Epidémiologie, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Cérébrovasculaire pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie
Mots-clés Pascal anglais : Carbon disulfide, Toxicity, Mortality, Stroke, Occupational exposure, Occupational medicine, Textile industry, Human, Epidemiology, Nervous system diseases, Central nervous system disease, Cerebral disorder, Cerebrovascular disease, Cardiovascular disease, Vascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0398361
Code Inist : 002B03L06. Création : 10/04/1997.