Base documentaire
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A prospective study of syphilis and HIV infection among injection drug users receiving methadone in the Bronx, NY. 
AMERICAN JOURNAL OF PUBLIC HEALTH, vol. 86, n° 8, PART1, 1996, pages 1112-1115, 31 réf., ISSN 0090-0036, USA
GOUREVITCH (M.N.), HARTEL (D.), SCHOENBAUM (E.E.), SELWYN (P.A.), DAVENNY (K.), FRIEDLAND (G.H.), KLEIN (R.S.)
Montefiore Medical Center. Albert Einstein College of Medicine. Bronx NY. USA
Objectives
The purposes of this study was to assess the relationship between syphilis and human immunodeficiency virus (HIV) infection in injection drug users.
Methods
A 6-year prospective study of 790 injection drug users receiving methadone maintenance treatment in the Bronx, NY, was conducted.
Results
Sixteen percent (4/25) of HIV-seroconverting patients, 4.8% (16/335) of prevalent HIV-seropositive patients, and 3.5% (15/430) of persistently HIV-seronegative patients were diagnosed with syphilis.
Incidence rates for early syphilis (cases per 1000 person-years) were 15.9 for HIV-seroconverting patients, 8.9 for prevalent HIV-seropositive patients, and 2.9 for persistently HIV-seronegative patients.
Early syphilis incidence was higher among women than men (8.4 vs 3.2 cases per 1000 person-years).
Independent risks for early syphilis included multiple sex partners, HIV seroconversion, paid sex, and young age.
All HIV seroconverters with syphilis were female.
Conclusions
Diagnosis of syphilis in drug-using women reflects high-risk sexual activity and is associated with acquiring HIV infection.
Interventions to reduce the risk of sexually acquired infections are urgently needed among female drug users.
Mots-clés BDSP : Syphilis, Bactériose, Infection, Epidémiologie, Virose, Prise de risque, Toxicomanie, Homme, Sexe, Age, Etats Unis, Amérique, Maladie autoimmune, Sida
Mots-clés Pascal : Syphilis, Tréponématose, Spirochétose, Bactériose, Infection, Epidémiologie, SIDA, Virose, Comportement sexuel, Prise risque, Toxicomanie, Voie intraveineuse, Homme, Sexe, Age, New York, Etats Unis, Amérique du Nord, Amérique, Maladie sexuellement transmissible, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : Syphilis, Treponematosis, Spirachaetosis, Bacteriosis, Infection, Epidemiology, AIDS, Viral disease, Sexual behavior, Risk taking, Drug addiction, Intravenous administration, Human, Sex, Age, New York, United States, North America, America, Sexually transmitted disease, Immunopathology, Immune deficiency
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Code Inist : 002B05F01. Création : 10/04/1997.
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