The purposes of this study was to assess the relationship between syphilis and human immunodeficiency virus (HIV) infection in injection drug users.
A 6-year prospective study of 790 injection drug users receiving methadone maintenance treatment in the Bronx, NY, was conducted.
Sixteen percent (4/25) of HIV-seroconverting patients, 4.8% (16/335) of prevalent HIV-seropositive patients, and 3.5% (15/430) of persistently HIV-seronegative patients were diagnosed with syphilis.
Incidence rates for early syphilis (cases per 1000 person-years) were 15.9 for HIV-seroconverting patients, 8.9 for prevalent HIV-seropositive patients, and 2.9 for persistently HIV-seronegative patients.
Early syphilis incidence was higher among women than men (8.4 vs 3.2 cases per 1000 person-years).
Independent risks for early syphilis included multiple sex partners, HIV seroconversion, paid sex, and young age.
All HIV seroconverters with syphilis were female.
Diagnosis of syphilis in drug-using women reflects high-risk sexual activity and is associated with acquiring HIV infection.
Interventions to reduce the risk of sexually acquired infections are urgently needed among female drug users.
Mots-clés Pascal : Syphilis, Tréponématose, Spirochétose, Bactériose, Infection, Epidémiologie, SIDA, Virose, Comportement sexuel, Prise risque, Toxicomanie, Voie intraveineuse, Homme, Sexe, Age, New York, Etats Unis, Amérique du Nord, Amérique, Maladie sexuellement transmissible, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : Syphilis, Treponematosis, Spirachaetosis, Bacteriosis, Infection, Epidemiology, AIDS, Viral disease, Sexual behavior, Risk taking, Drug addiction, Intravenous administration, Human, Sex, Age, New York, United States, North America, America, Sexually transmitted disease, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0396285
Code Inist : 002B05F01. Création : 10/04/1997.