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  1. Fulltext. Directly observed therapy for tuberculosis in rural South Africa, 1991 through 1994.

    Article - En anglais



    This paper describes an audit of a community-based tuberculosis treatment program involving directly observed therapy in South Africa.


    A program audit of 2473 consecutive tuberculosis patients in Hlabisa Health District, KwaZulu/Natal, South Africa, was conducted between 1991 and 1994.


    Monthly admissions increased from 34 per month in 1991 to 66 in 1994.

    Of 2186 patients managed in Hlabisa, 1903 (87%) received directly observed therapy.

    Of those receiving directly observed therapy, 1034 (55%) were supervised by volunteers ; 743 (72%) of these were supervised by storekeepers.

    Among those patients managed locally, 1679 (85%) of 1967 surviving patients completed treatment.

    Completion rates for patients supervised by health workers and non-health workers were the same.

    Completion fell from a high of 90% in 1992 to 78% in 1994.

    Mortality increased from 5% in 1991 to 10% in 1994.


    Community-based directly observed therapy that uses an intermittent drug regime and volunteers as supervisors can achieve high treatment completion rates for tuberculosis, even in resource-poor settings.

    Mots-clés Pascal : Tuberculose, Mycobactériose, Bactériose, Infection, Chimiothérapie, Antituberculeux, Traitement, Milieu rural, République Sud Africaine, Afrique, Diagnostic, Observance médicamenteuse, Superviseur, Homme, Evaluation, Programme sanitaire, Santé communautaire

    Mots-clés Pascal anglais : Tuberculosis, Mycobacterial infection, Bacteriosis, Infection, Chemotherapy, Antituberculous agent, Treatment, Rural environment, South Africa, Africa, Diagnosis, Drug compliance, Supervisor, Human, Evaluation, Sanitary program, Community health

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0396282

    Code Inist : 002B02S07. Création : 10/04/1997.