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  1. Shift work, nitrous oxide exposure and subfertility among Swedish midwives.

    Article - En anglais


    Shift work and nitrous oxide exposure have both been suspected of having adverse influence on the reproductive performance of health workers.

    Time to pregnancy has been suggested as a sensitive measure of fecundity in occupationally exposed groups.

    We investigated the effects of shift work and nitrous oxide exposure on the fertility of Swedish midwives.


    A questionnaire was mailed to all members of the Swedish Midwives Association who were born 1940 or thereafter, 3985 in all.

    Eighty-four per cent responded.

    Detailed information on the number of menstrual cycles required to achieve pregnancy and the working conditions during that period were obtained concerning the most recent, planned pregnancy occurring after 1983.

    The per cycle probability of becoming pregnant was calculated for each exposure category, and the relation to the unexposed was expressed as fecundability ratios.


    Midwives who worked two-shift, three-shift rotas, or only nights had reduced fertility compared to those working in the day time.

    The fecundability ratios were 0.78 (95% confidence interval [CI] : 0.65-0.94), 0.77 (95% CI : 0.60-0.98), and 0.82 (95% CI : 0.64-1.03), respectively, after adjustment for covariates.

    No effect of nitrous oxide exposure was noted except in the small group reporting that they assisted at more than 30 deliveries per month when nitrous oxide was used (fecundability ratio=0.64 ; 95% CI : 0.44-0.95).



    Mots-clés Pascal : Azote protoxyde, Anesthésique général, Composé volatil, Exposition professionnelle, Travail posté, Toxicité, Fertilité, Femme, Homme, Sage femme, Suède, Europe, Epidémiologie, Condition travail, Médecine travail, Personnel sanitaire, Gaz

    Mots-clés Pascal anglais : Nitrogen protoxide, General anesthetic, Volatile compound, Occupational exposure, Shift work, Toxicity, Fertility, Woman, Human, Midwife, Sweden, Europe, Epidemiology, Working condition, Occupational medicine, Health staff, Gases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0390166

    Code Inist : 002B02U10. Création : 10/04/1997.