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  1. Low prevalence of hepatitis C infection in hepatocellular carcinoma (HCC) cases and population controls in Guangxi, a hyperendemic region for HCC in the People's Republic of China.

    Article - En anglais

    Southern Guangxi, China has one of the highest incidences of hepatocellular carcinoma (HCC) in the world.

    Serum samples collected from subjects of an earlier case - control study (39 cases, 41 controls) and from a random sampling of a residential male cohort (n=100) were tested for antibodies for the hepatitis C virus (anti-HCV) using ELISA version 2.0 with confirmation by RIBA version 2.0. Only one of 141 (0.7%, upper 95% confidence limit, 3.2%) control subjects and none of 39 (upper 95% confidence limit. 6.07%) HCC cases tested positive for anti-HCV.

    Our results indicate that hepatitis C infection is not an important environmental determinant of HCC risk in this hyperendemic region.

    Mots-clés Pascal : Carcinome hépatocellulaire, Facteur risque, Epidémiologie, Hépatite virale C, Virose, Infection, Chine, Asie, Sud, Endémie, Prévalence, Homme, Appareil digestif pathologie, Foie pathologie, Tumeur maligne

    Mots-clés Pascal anglais : Liver cell carcinoma, Risk factor, Epidemiology, Viral hepatitis C, Viral disease, Infection, China, Asia, South, Endemy, Prevalence, Human, Digestive diseases, Hepatic disease, Malignant tumor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0377184

    Code Inist : 002B13C01. Création : 10/04/1997.