logo BDSP

Base documentaire

  1. Factors associated with surgical and radiation therapy for early stage breast cancer in older women.

    Article - En anglais


    In addition to demographic and health care-related characteristics, the age and physiologic status of women at the time of breast cancer diagnosis have been reported to influence receipt of standard treatments.

    Previous studies of the influence of age and comorbidity have not examined whether other patient-region-or health care-related characteristics altered the association of age and comorbidity with type of treatment received.


    This study examined factors associated with receipt of breast-conserving surgery and radiation therapy, both of which are recommended treatments for breast cancer, among a cohort of 18 704 women aged 65 years or more who had breast cancer diagnosed during the period from 1985 through 1989.


    A data file linking Medicare claims records to data from the Surveillance, Epidemiology, and End Results (SEER) Program of the U.S. National Cancer Institute was utilized.

    Logistic regression analysis was used to examine associations between patient, region, and hospital characteristics and the receipt of specific treatments.

    The likelihood test was used to assess the significance of observed associations (expressed as odds ratios [ORs]). Because of multiple comparisons, only those ORs with two-sided P values<. 01 were considered statistically significant.


    The frequency of breast-conserving surgery was highest (54%) among women aged 80 years or more, who had two or more comorbid conditions and stage I disease. (...)

    Mots-clés Pascal : Tumeur maligne, Glande mammaire, Chirurgie conservatrice, Radiothérapie, Modalité traitement, Age, Etude statistique, Etude cohorte, Epidémiologie, Vieillard, Homme, Femelle, Stade précoce, Glande mammaire pathologie

    Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Conservative surgery, Radiotherapy, Application method, Age, Statistical study, Cohort study, Epidemiology, Elderly, Human, Female, Early stage, Mammary gland diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0376731

    Code Inist : 002B20E02. Création : 10/04/1997.