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  1. Representation of African-Americans, Hispanics, and Whites in National Cancer Institute cancer treatment trials.

    Article - En anglais


    The National Cancer Institute (NCI) - sponsored clinical trials cooperative groups place more than 25 000 American patients in treatment trials every year.

    Equal access and proportional representation of all races/ethnicities is desired.


    Our objectives were to evaluate the inclusion of African-Americans, Hispanics, and non-Hispanic whites in NCI-sponsored treatment trials and to determine if there is proportional racial/ethnic representation.


    During the period of January 1,1991, through June 30,1994,99 495 cancer patients were enrolled in clinical trials and declared themselves as non-Hispanic black, non-Hispanic white, or Hispanic (of any race).

    In the analysis, participants in NCI treatment trials were subdivided into three age groups : birth to 19 years, 20-49 years, and 50 or more years.

    The racial/ethnic composition of each of these age groups was compared with the racial/ethnic makeup of the American population with cancer.

    Estimates of the number of incident cancer cases per year were made for each racial/ethnic group within each age group using data from the Surveillance, Epidemiology, and End Results (SEER) Program and the 1990 Census.

    The percentage of all cancer patients who were in each racial/ethnic group were compared with the population that entered clinical trials.

    Comparisons are also made separately for patients with leukemia and breast, colorectal, lung, and prostate cancers. (...)

    Mots-clés Pascal : Tumeur maligne, Homme, Anticancéreux, Traitement, Essai clinique, Recrutement population, Race, Ethnie, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Représentativité

    Mots-clés Pascal anglais : Malignant tumor, Human, Antineoplastic agent, Treatment, Clinical trial, Population recruitment, Race, Ethnic group, United States, North America, America, Epidemiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0376727

    Code Inist : 002B02R02. Création : 10/04/1997.