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  1. Identifying environmental risk to male reproductive function by occupational sperm studies : logistics and design options.

    Article - En anglais

    Malfunction of the male reproductive system might be a sensitive marker of environmental hazards, the effects of which may extend beyond reproductive function.

    The testis is more vulnerable to heat and ionising radiation than any other organ of the body and several xenobiotics are known to disrupt spermatogenesis after low level exposure.

    Studies of environmental impact on human health are often most informative and accurate when carried out in the workplace where exposures can be high and easy to document.

    Semen analysis provides readily obtainable information on testicular function.

    The main advantages in comparison with functional measures such as fertility rates and time taken to conceive are the possibilities to examine men independently of marriage and pregnancy, to find changes of fecundity with different exposures within the same person and to detect adverse effects when no alteration of fertility is yet taking place.

    In the implementation of an occupational sperm study considerable attention must be paid to logistic issues.

    A mobile laboratory unit for initial semen preparation and processing may in some situations increase worker compliance and the quality of sperm cell motility. (...)

    Mots-clés Pascal : Chaleur, Agent physique, Rayonnement ionisant, Exposition professionnelle, Médecine travail, Homme, Mâle, Lieu travail, Marqueur biologique, Spermatozoïde, Testicule, Toxicité, Composé chimique, Etude longitudinale, Appareil génital mâle pathologie, Facteur risque

    Mots-clés Pascal anglais : Heat, Physical agent, Ionizing radiation, Occupational exposure, Occupational medicine, Human, Male, Work place, Biological marker, Spermatozoa, Testicle, Toxicity, Chemical compound, Follow up study, Male genital diseases, Risk factor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0376238

    Code Inist : 002A08F02. Création : 10/04/1997.