Epidemiological appraisal of studies of residential exposure to power frequency magnetic fields and adult cancers.
Objectives-To appraise epidemiological evidence of the purported association between residential exposure to power frequency magnetic fields and adult cancers.
Methods-Literature review and epidemiological evaluation.
Seven epidemiological studies have been conducted on the risk of cancer among adults in relation to residential exposure to power frequency magnetic fields.
Leukaemia was positively associated with magnetic fields in three case-control studies.
The other two case-control studies and two cohort studies did not show such a link.
Brain tumours and breast cancer have rarely been examined by these studies.
Based on the epidemiological results, the analysis of the role of chance and bias, and the criteria for causal inferences, it seems that the evidence is not strong enough to support the putative causal relation between residential exposure to magnetic fields and adult leukaemia, brain tumours, or breast cancer.
Inadequate statistical power is far more a concern than selection bias, information bias, and confounding in interpreting the results from these studies, and in explaining inconsistencies between studies.
Conclusions-Our reviews suggested that the only way to answer whether residential exposure to magnetic fields is capable of increasing the risks of adult cancers is to conduct more studies carefully avoiding methodological flaws, in particular small sample size. (...)
Mots-clés Pascal : Champ magnétique, Haute fréquence, Toxicité, Zone résidentielle, Homme, Epidémiologie, Carcinogène, Tumeur maligne, Adulte
Mots-clés Pascal anglais : Magnetic field, High frequency, Toxicity, Residential zone, Human, Epidemiology, Carcinogen, Malignant tumor, Adult
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0372543
Code Inist : 002A08E. Création : 10/04/1997.