Skin prick tests and specific IgE in adults from three different areas of Sweden.
The aims of this part of the European Respiratory Health Survey were to estimate the prevalence of atopic sensitization to inhalant allergens among adults in three different areas of Sweden and to investigate the association between sensitization and certain risk factors.
Randomly selected subjects aged 20-46 years from Göteborg, Uppsala, and Västerbotten were investigated with the skin prick test (SPT), analyses for specific IgE antibodies in serum (specific IgE) and total serum immunoglobulin E (total IgE), and a questionnaire.
SPT was performed in 1572 subjects and analyses of specific IgE in 1470.
One or more positive SPT were found in 35.6% and one or more positive specific IgE in 31.7% - approximately the same values in all three areas.
Birch, grass, cat, and dog were the most frequent sensitizing agents and occurred at similar prevalences, i.e., around 15%, in all areas.
The SPT to mite was positive in 14.1% in Göteborg, 7.4% in Uppsala, and 7.9% in Västerbotten.
A positive SPT to pellitory of the wall (Parietaria), not described previously in Sweden, was found in 3.4% in Göteborg.
Living in Göteborg was independently associated with a higher risk of a positive SPT to mite and Parietaria.
Heredity, male sex, and low age were independently associated with atopy.
Birth in the Scandinavian countries was independently associated with sensitization to cat, whereas birth in other countries was associated with sensitization to mite. (...)
Mots-clés Pascal : Atopie, Prévalence, Facteur risque, Epidémiologie, Test cutané, Prick test, Sérologie, IgE, Suède, Europe, Adulte, Homme, Exploration immunologique, Immunopathologie, Allergie
Mots-clés Pascal anglais : Atopy, Prevalence, Risk factor, Epidemiology, Skin test, Prick test, Serology, IgE, Sweden, Europe, Adult, Human, Immunological investigation, Immunopathology, Allergy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0355992
Code Inist : 002B06C01. Création : 10/04/1997.