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  1. Aetiology of childhood cataract in south India.

    Article - En anglais

    Aim-To identify the causes of childhood cataract in south India with emphasis on factors that might be potentially preventable.

    Methods-A total of 514 consecutive children with cataract attending an eye hospital outpatient clinic were examined and their parents interviewed by a trained interviewer using a standardised questionnaire in the local language.

    Serology was performed on children under 1 year of age to detect congenital rubella syndrome (CRS).

    Other investigations were performed as clinically indicated.


    Of the 366 children with non-traumatic cataract 25% were hereditary, 15% were due to congenital rubella syndrome, and 51% were undetermined.

    In children under 1 year of age 25% were due to rubella and cataract of nuclear morphology had a 75% positive predictive value for CRS.

    Mothers of children in the undetermined group were more likely to have taken abortifacients than a group of age matched controls (p=0.1) but use of other medications in pregnancy was similar in both groups.

    Of the 148 (29%) children with traumatic cataracts three quarters were over the age of 6 years.

    Stick injuries were responsible for 28%, thorn injuries for 21%, and firecrackers for 5%. Conclusion-Nearly half of non-traumatic cataract in south India is due to potentially preventable causes (CRS and autosomal dominant disease). (...)

    Mots-clés Pascal : Cataracte, Enfant, Homme, Etiologie, Inde, Asie, Oeil pathologie, Cristallin pathologie, Segment antérieur pathologie

    Mots-clés Pascal anglais : Cataract, Child, Human, Etiology, India, Asia, Eye disease, Lens disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0355983

    Code Inist : 002B09G. Création : 10/04/1997.