Aim-To identify the causes of childhood cataract in south India with emphasis on factors that might be potentially preventable.
Methods-A total of 514 consecutive children with cataract attending an eye hospital outpatient clinic were examined and their parents interviewed by a trained interviewer using a standardised questionnaire in the local language.
Serology was performed on children under 1 year of age to detect congenital rubella syndrome (CRS).
Other investigations were performed as clinically indicated.
Of the 366 children with non-traumatic cataract 25% were hereditary, 15% were due to congenital rubella syndrome, and 51% were undetermined.
In children under 1 year of age 25% were due to rubella and cataract of nuclear morphology had a 75% positive predictive value for CRS.
Mothers of children in the undetermined group were more likely to have taken abortifacients than a group of age matched controls (p=0.1) but use of other medications in pregnancy was similar in both groups.
Of the 148 (29%) children with traumatic cataracts three quarters were over the age of 6 years.
Stick injuries were responsible for 28%, thorn injuries for 21%, and firecrackers for 5%. Conclusion-Nearly half of non-traumatic cataract in south India is due to potentially preventable causes (CRS and autosomal dominant disease). (...)
Mots-clés Pascal : Cataracte, Enfant, Homme, Etiologie, Inde, Asie, Oeil pathologie, Cristallin pathologie, Segment antérieur pathologie
Mots-clés Pascal anglais : Cataract, Child, Human, Etiology, India, Asia, Eye disease, Lens disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0355983
Code Inist : 002B09G. Création : 10/04/1997.