There is limited information regarding the clinical manifestations of human immunodeficiency virus (HIV) infection among adolescents.
To better define the clinical presentation and course of HIV disease in this population, a retrospective review of all HIV-infected persons age 13-21 years at entry into a public, inner-city HIV outpatient clinic in New Orleans, Louisiana, was undertaken.
A total of 141 adolescents were included in this study.
The cohort was predominantly female (65%) and African-American (83%), and acquired HIV infection through sexual contact (89%). As many as 75% of the females and 48% of the males were diagnosed with at least one sexually transmitted disease (STD), respectively, and young African-American females with a CD4 cell count>500/mm3 were at highest risk.
The proportions of female adolescents having a gravida = 1 and 2 were 82% and 20%, respectively.
A total of 55% of females were diagnosed with squamous intraepithelial lesions (SIL) at least once.
Similar to adults, the majority of opportunistic processes occurred in adolescents with a CD4 cell count<200/mm3.
Known HIV-related symptoms (oral hairy leukoplakia, thrush, and zoster) were significantly predictive (p<. 0001) for HIV disease progression.
Although HIV-related symptoms and infections do not appear to be unique in the adolescent population, it is clear that STDs and pregnancies are common among female adolescents. (...)
Mots-clés Pascal : SIDA, Virose, Infection, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Immunopathologie, Immunodéficit, Symptomatologie, Adolescent, Homme, Evolution, Facteur risque, Maladie sexuellement transmissible, Gestation, Infection opportuniste
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Immunopathology, Immune deficiency, Symptomatology, Adolescent, Human, Evolution, Risk factor, Sexually transmitted disease, Pregnancy, Opportunistic infection
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0355147
Code Inist : 002B06D01. Création : 10/04/1997.