Data from a retrospective cohort study of people with adolescent idiopathic scoliosis were combined with information on full-spinal radiographs to estimate contemporary x-ray doses and life-time risks for development of cancer.
To project the lifetime risk for development of cancer from diagnostic radiographs for people with adolescent idiopathic scoliosis.
Although a twofold excess risk for breast cancer has been reported for women treated for scoliosis between 1925 and 1965, information on the cancer risks associated with scoliosis management today is sparse.
Specifically, there is a lack of up-to-date information on the number of spinal radiographs taken, the organ-specific x-ray doses from current radiographic techniques, and the projected cancer risks.
The cohort consisted of subjects with adolescent idiopathic scoliosis who were referred to the scoliosis clinic of a large pediatric hospital between 1965 and 1979 in Montreal, Quebec, Canada.
Based on radiographic equipment and practices implemented in 1982, organ-specific x-ray doses to the thyroid gland, female breast, respiratory organs, digestive organs, and bone marrow were calculated using Monte Carlo methods.
These doses were incorporated into a life table procedure to calculate theoretic lifetime cancer risks. (...)
Mots-clés Pascal : Scoliose, Adolescent, Homme, Facteur risque, Complication, Tumeur maligne, Hémopathie maligne, Radiographie, Irradiation, Rayonnement ionisant, Epidémiologie, Québec, Canada, Amérique du Nord, Amérique, Rachis, Système ostéoarticulaire pathologie, Rachis pathologie, Déformation, Exploration radiologique
Mots-clés Pascal anglais : Scoliosis, Adolescent, Human, Risk factor, Complication, Malignant tumor, Malignant hemopathy, Radiography, Irradiation, Ionizing radiation, Epidemiology, Quebec, Canada, North America, America, Spine, Diseases of the osteoarticular system, Spine disease, Deformation, Radiologic investigation
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0351869
Code Inist : 002B15F. Création : 10/04/1997.