Unapproved use of approved drugs : The physician, the package insert, and the food and drug administration : Subject review.
Physicians who prescribe a new drug that has not been approved for a specific indication or a specific age group frequently find themselves in a quandary.
Physicians who prescribe « old, » time-honored drugs usually do not consult the package insert or search for US Food and Drug Administration (FDA) approval.
This statement was written to clarify the legal and informational status of the package insert and the role of the FDA in approving or not approving drugs for specific indications or specific age groups.
The unapproved use of approved drugs, or so-called « off-label » use, is extremely prevalent among physicians who care for children.
It is important that such use of compounds be brought up to date with current FDA policies and to emphasize the responsibility of the prescribing physician in the use of these compounds.
Mots-clés Pascal : Médicament, Autorisation, Prescription médicale, Responsabilité professionnelle, Législation, Article synthèse, Homme
Mots-clés Pascal anglais : Drug, Licence procedure, Medical prescription, Occupational responsibility, Legislation, Review, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0351310
Code Inist : 002B30A09. Création : 10/04/1997.