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  1. Epidemiological aspects of inflammatory bowel disease in a north Italian population : a 4-year prospective study.

    Article - En anglais

    Objective 

    To determine the incidence and clinical characteristics at presentation of inflammatory bowel disease (IBD) in a defined area of north Italy.

    Design 

    A 4-year prospective population-based epidemiological study.

    Setting 

    An area in Lombardia defined by the National Health Service scheme with about 294000 inhabitants, two referral hospitals and 259 general practitioners (GPs).

    Patients 

    Subjects presenting to a GP with symptoms compatible with IBD underwent a diagnostic work-up at one of the referral hospitals.

    Those with ulcerative colitis (UC), Crohn's disease (CD) or indeterminate colitis diagnosed according to a defined protocol were included, as were residents of the area with IBD diagnosed elsewhere.

    Rigid case ascertainment methods were used

    Patients were followed for one year ; 125 patients were identified.

    Results 

    The patient ascertainment rate was constant over the 4 years ; UC was diagnosed in 82 patients, CD in 40, and indeterminate colitis in three.

    The mean annual incidence of IBD for the whole period was 10.6/105 inhabitants (95% confidence limits, 7.2-15.1), 7.0/105 for UC (4.3-10.7) and 3.4/105 (1.6-6.3) for CD.

    The mean interval between onset of symptoms and diagnosis was under 6 months.

    The clinical characteristics of our patients were similar to those of north European and American series. (...)

    Mots-clés Pascal : Rectocolite ulcérohémorragique, Entérite Crohn, Incidence, Facteur risque, Symptomatologie, Epidémiologie, Homme, Lombardie, Italie, Europe, Appareil digestif pathologie, Intestin pathologie, Maladie inflammatoire

    Mots-clés Pascal anglais : Ulcerative colitis, Crohn disease, Incidence, Risk factor, Symptomatology, Epidemiology, Human, Lombardy, Italy, Europe, Digestive diseases, Intestinal disease, Inflammatory disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0346625

    Code Inist : 002B13B03. Création : 10/04/1997.