To determine the incidence and clinical characteristics at presentation of inflammatory bowel disease (IBD) in a defined area of north Italy.
A 4-year prospective population-based epidemiological study.
An area in Lombardia defined by the National Health Service scheme with about 294000 inhabitants, two referral hospitals and 259 general practitioners (GPs).
Subjects presenting to a GP with symptoms compatible with IBD underwent a diagnostic work-up at one of the referral hospitals.
Those with ulcerative colitis (UC), Crohn's disease (CD) or indeterminate colitis diagnosed according to a defined protocol were included, as were residents of the area with IBD diagnosed elsewhere.
Patients were followed for one year ; 125 patients were identified.
The patient ascertainment rate was constant over the 4 years ; UC was diagnosed in 82 patients, CD in 40, and indeterminate colitis in three.
The mean annual incidence of IBD for the whole period was 10.6/105 inhabitants (95% confidence limits, 7.2-15.1), 7.0/105 for UC (4.3-10.7) and 3.4/105 (1.6-6.3) for CD.
The mean interval between onset of symptoms and diagnosis was under 6 months.
The clinical characteristics of our patients were similar to those of north European and American series. (...)
Mots-clés Pascal : Rectocolite ulcérohémorragique, Entérite Crohn, Incidence, Facteur risque, Symptomatologie, Epidémiologie, Homme, Lombardie, Italie, Europe, Appareil digestif pathologie, Intestin pathologie, Maladie inflammatoire
Mots-clés Pascal anglais : Ulcerative colitis, Crohn disease, Incidence, Risk factor, Symptomatology, Epidemiology, Human, Lombardy, Italy, Europe, Digestive diseases, Intestinal disease, Inflammatory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0346625
Code Inist : 002B13B03. Création : 10/04/1997.