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  1. Increased limbic system symptomatology and sensitizability of young adults with chemical and noise sensitivities.

    Article - En anglais

    We previously hypothesized that individual differences in (a) limbic system reactivity and (b) central nervous system sensitizability underlie vulnerability to environmental stimuli, not only in the controversial clinical condition multiple chemical sensitivity (MCS), but also in the general population.

    Earlier research has shown overlaps in the characteristics of persons who report noise and air pollutant sensitivities.

    This study assessed questionnaire responses of 897 young adult college students who reported high versus low frequency of illness from several environmental chemical odors and concomitantly high versus low sensitivity to environmental noise.

    Subjects who reported increased rates of illness from chemical odors with or without noise sensitivity scored significantly higher (P<0.0001) on a measure of limbic system symptomatology derived from ictal sensory, somatic, mnemonic, and behavioral manifestations of temporal lobe epilepsy.

    The group rating high both for illness from chemicals and for noise sensitivity had characteristics predictive of heightened sensitizability from the animal research on timedependent sensitization (progressive response amplification to repeated, intermittent stimuli over time) : i.e., higher female to male ratio (gender risk factor), increased rates of drug abuse problems in blood relatives (genetic risk factor), trait shyness (hyperreactivity to novelty), and increased carbohydrate craving. (...)

    Mots-clés Pascal : Composé chimique, Bruit, Sensibilité, Adulte jeune, Homme, Comparaison interindividuelle, Questionnaire, Epidémiologie, Odeur, Etiologie, Système limbique, Arizona, Etats Unis, Amérique du Nord, Amérique, Mode de vie, Etat dépressif, Hypersensibilité, Syndrome intolérance composé chimique, Cacosmie

    Mots-clés Pascal anglais : Chemical compound, Noise, Sensitivity, Young adult, Human, Interindividual comparison, Questionnaire, Epidemiology, Odor, Etiology, Limbic system, Arizona, United States, North America, America, Life habit, Depression, Hypersensitivity

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0340457

    Code Inist : 002B30A02B. Création : 10/04/1997.