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  1. Epidemiology of cholelithiasis in southern Italy. Part II : Risk factors.

    Article - En anglais


    To determine behavioural, dietary and other common factors associated with new cases of gallstones, diagnosed by ultrasonography, in a prospective cohort study conducted in southern Italy.

    Subjects and methods 

    Between May 1985 and June 1986, systematic sampling from the electoral register of Castellana, a small town in southern Italy, yielded 2472 subjects who had had their gall-bladder checked for gallstones by ultrasonography.

    Between May 1992 and June 1993,1962 out of the 2235 (87.7%) subjects without gallstones at baseline agreed to a further ultrasound examination.

    At the first survey a standardized questionnaire was administered, inquiring about medical history, diet, cigarette smoking and other behavioural characteristics.

    Height and weight were also measured, and blood levels of glucose, cholesterol, HDL-cholesterol and triglycerides were determined by standard methods.

    The same variables were measured at the second survey.

    The diagnosis of gallstones was made with the same echograph by echographists working in the same department.

    Multiple logistic regression was used to determine which factors measured at the first survey were associated with the incident cases of gallstones.


    One hundred and four subjects had developed gallstones, an incidence of 9.7 per 1000 persons per year. (...)

    Mots-clés Pascal : Lithiase, Vésicule biliaire, Prévalence, Facteur risque, Comportement, Coutume alimentaire, Indice masse corporelle, Consommation, Alcool, Chimiothérapie, Toxicité, Epidémiologie, Homme, Italie, Europe, Voie biliaire pathologie, Appareil digestif pathologie

    Mots-clés Pascal anglais : Lithiasis, Gallbladder, Prevalence, Risk factor, Behavior, Food habit, Body mass index, Consumption, Alcohol, Chemotherapy, Toxicity, Epidemiology, Human, Italy, Europe, Biliary tract disease, Digestive diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0336432

    Code Inist : 002B13C03. Création : 10/04/1997.