A study of the quality of life and cost-utility of renal transplantation.
The objective of this study was to assess the cost-utility of renal transplantation compared with dialysis.
To accomplish this, a prospective cohort of pre-transplant patients were followed for up to two years after renal transplantation at three University-based Canadian hospitals.
A total of 168 patients were followed for an average of 19.5 months after transplantation.
Health-related quality of life was assessed using a hemodialysis questionnaire, a transplant questionnaire, the Sickness Impact Profile, and the Time Trade-Off Technique.
Fully allocated costs were determined by prospectively recording resource use in all patients.
A societal perspective was taken.
By six months after transplantation, the mean health-related quality of life scores of almost all measures had improved compared to pre-transplantation, and they stayed improved throughout the two years of follow up.
The mean time trade-off score was 0.57 pre-transplant and 0.70 two years after transplantation.
The proportion of individuals employed increased from 30% before transplantation to 45% two years after transplantation.
Employment prior to transplantation [relative risk (RR)=23], graft function (RR 10) and age (RR 1.6 for every decrease in age by one decade), independently predicted employment status after transplantation. (...)
Mots-clés Pascal : Insuffisance rénale, Chronique, Homme, Transplantation, Traitement, Qualité vie, Echelle évaluation, Questionnaire, Analyse coût, Appareil urinaire pathologie, Rein pathologie, Chirurgie, Economie santé
Mots-clés Pascal anglais : Renal failure, Chronic, Human, Transplantation, Treatment, Quality of life, Evaluation scale, Questionnaire, Cost analysis, Urinary system disease, Renal disease, Surgery, Health economy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0333163
Code Inist : 002B25H. Création : 10/04/1997.