Diisocyanates, highly reactive monomers which cross-link polyurethane, are the most widely recognized causes of occupational asthma.
Many exposed workers are end-users, including autobody spray painters who form a large population at risk.
Neither the factors which determine incidence rate nor strategies for control have been adequately studied in this setting.
We have conducted a cross-sectional survey of 23 (about one in five) autobody shops in the New Haven area to determine the feasibility of clinical epidemiological studies in this population.
Among 102 workers, there was a high rate of airway symptoms consistent with occupational asthma (19.6%). Symptoms were most prevalent among those with the greatest opportunity for exposure (dedicated spray painters) and least among office workers ; part-time painters had intermediate rates.
Atopy was not associated with risk while smoking seemed to correlate with symptoms.
Regular use of air-supplied respirators appeared to be associated with lower risk among workers who painted part-or full-time.
We were unable to validate the questionnaire responses with peak expiratory flow record data attempted on a 1/3 sample of the workers.
Despite intensive training and effort, subject compliance was limited.
Among those who provided adequate data (24 of 38), only two demonstrated unequivocal evidence of labile airways ; two others demonstrated lesser changes consistent with an occupational effect on flow rates. (...)
Mots-clés Pascal : Pulvérisation, Peinture, Isocyanate organique, Exposition professionnelle, Homme, Asthme, Industrie automobile, Médecine travail, Toxicité, Débit expiratoire, Questionnaire, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Allergie, Immunopathologie
Mots-clés Pascal anglais : Spraying, Paint, Organic isocyanate, Occupational exposure, Human, Asthma, Automobile industry, Occupational medicine, Toxicity, Expiratory flow rate, Questionnaire, Respiratory disease, Obstructive pulmonary disease, Allergy, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0333012
Code Inist : 002B03L06. Création : 10/04/1997.