Objective To investigate the current levels of exposure of the Japanese population to cadmium and lead, in comparison with the levels in 1980s.
Design A nation wide survey was conducted in 1991-1994 (the 1990 study) in 19 study sites in Japan as a follow-up to a study conducted in 1979-1983 (the 1980 study).
Blood samples and 24-h total food duplicates were collected from women who did not smoke or drink habitually.
Methods Blood and food duplicates (after homogenization) were analysed for cadmium (Cd-B and Cd-F, respectively) and lead (Pb-B and Pb-F) by graphite furnace atomic absorption after wet-ashing.
Results Altogether, 467 women volunteered for blood sampling.
Of these women, 375 also gave food duplicates.
Geometric mean (GM) Cd-B levels in the 1990 study were lower than the corresponding 1980 values in most study sites so that the 1990 grand GM (1.98 ng/ml) for Cd-B was significantly lower than the 1980 GM (3.58 ng/ml).
This reduction in Cd-B was related to the reduction in Cd-F (GM for Cd-F was 38.0 mug/day in the 1980 study and 30.0 mug/day in the 1990 study).
Dietary intake was almost exclusively the route of Cd burden among the populations studied.
Both Pb-B and Pb-F also showed a remarkable reduction, i.e. from 33.9 ng/ml (1980 GM) to 23.2 ng/ml (1990 GM) in the case of Pb-B, and from 32.2 mug/day (1980 GM) to 7.1 mug/day (1990 GM) in the case of Pb-F. (...)
Mots-clés Pascal : Cadmium, Plomb, Métal lourd, Taux, Sang, Epidémiologie, Evolution, Contamination, Riz, Pollution, Santé et environnement, Japon, Asie, Homme, Alimentation
Mots-clés Pascal anglais : Cadmium, Lead, Heavy metal, Rate, Blood, Epidemiology, Evolution, Contamination, Rice, Pollution, Health and environment, Japan, Asia, Human, Feeding
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0328973
Code Inist : 002B03L05. Création : 10/04/1997.