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  1. Economic analysis of treating depression with nefazodone v. imipramine.

    Article - En anglais

    Background

    It is estimated that treating diagnosed depression costs £420 million annually in England and Wales.

    This economic study analyses treatment of major depression with nefazodone v. imipramine.

    Method

    The study updates a previously published model using data obtained from the continuation phase of a double-blind one-year placebo-controlled comparison of nefazodone with imipramine.

    Results

    Annual costs for nefazodone are lower than those for imipramine, £218 compared to £254 ; the cost per successfully treated patient is also lower for nefazodone than for imipramine, £242 v. £323.

    Varying the resources included in the treatment patterns still results in lower costs for nefazodone treatment.

    Conclusions

    Based on clinical trial data for patients completing six to eight weeks of depression treatment and followed for at least one year, the model shows that the annual costs of nefazodone are lower than those for the less expensive imipramine.

    Mots-clés Pascal : Imipramine, Néfazodone, Etude comparative, Analyse coût, Economie santé, Chimiothérapie, Traitement, Composé tricyclique, Antagoniste, Récepteur sérotoninergique 5-HT2, Inhibiteur recapture, Sérotonine, Homme, Etat dépressif, Trouble humeur

    Mots-clés Pascal anglais : Comparative study, Cost analysis, Health economy, Chemotherapy, Treatment, Tricyclic compound, Antagonist, 5-HT2 receptor, Reuptake inhibitor, Serotonin, Human, Depression, Mood disorder

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0328330

    Code Inist : 002B02B02. Création : 10/04/1997.