logo BDSP

Base documentaire

  1. Serological examination of human and animal sera from six countries of three continents for the presence of rickettsial antibodies.

    Article - En anglais

    Forty samples each of human sera collected in Guinea Bissau, Cape Verde, El Salvador and Iran, and animal sera (goat and cattle from Sri Lanka and sheep from Tanzania) were examined for the presence of antibodies to typhus group (TG) rickettsiae, spotted fever group (SFG) rickettsiae and Coxiella burnetii by enzyme-linked immunosorbent assay (ELISA) and indirect fluorescent antibody (IFA) test.

    Of human sera tested, a higher proportion of positive sera were found with ELISA and IFA test for TG, SFG rickettsiae and C. burnetii in El Salvador (42.5 vs 20.0%, 40.0 vs 32.5%, and 27.5 vs 27.5%, respectively) and in Iran (25.0 vs 15.0%, 45.0 vs 27.5%, and 27.5 vs 25.0%, respectively), than in Guinea Bissau and Cape Verde, where they were less than 20.0% except for antibodies to SFG rickettsiae in Guinea Bissau (25.0% with ELISA and 20.0% with IFA test).

    While all animal sera were negative for the presence of antibodies to TO rickettsiae, a high proportion of sera from Sri Lanka reacted in ELISA and IFA test with SFG rickettsiae and C. burnetii (37.5 vs 20.0% and 27.5 vs 25.0% for goat sera, and 40.0 vs 30.0%, and 17.5 vs 15.0% for cattle sera, respectively).

    The results obtained indicate that the studied rickettsial diseases can be spread in given territories and may pose a public health problem requiring greater attention than has been paid so far.

    The suitability of ELISA and IFA test for serological survey of rickettsial antibodies is discussed.

    Mots-clés Pascal : Rickettsiose, Rickettsialose, Bactériose, Infection, Epidémiologie, Sérologie, Animal, Homme, Etude comparative, Technique ELISA, Immunofluorescence indirecte, Méthode étude, Iran, Asie, Iles Cap Vert, Iles Atlantiques, Guinée Bissau, Afrique, Salvador, Amérique Centrale, Amérique, Sri Lanka, Tanzanie

    Mots-clés Pascal anglais : Rickettsial infection, Rickettsialosis, Bacteriosis, Infection, Epidemiology, Serology, Animal, Human, Comparative study, ELISA assay, Indirect immunofluorescence, Investigation method, Iran, Asia, Cape Verde Islands, Atlantic Ocean Islands, Guinea-Bissau, Africa, El Salvador, Central America, America, Sri Lanka, Tanzania

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0324560

    Code Inist : 002B05B02L8. Création : 10/04/1997.