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  1. Risk factors of age-related maculopathy in a population 70 years of age or older.

    Article - En anglais

    Purpose 

    To evaluate possible risk factors for age-related maculopathy (ARM) in an epidemiologic cross-sectional population study of inhabitants 70 years of age or older in a rural area in Oulu County, Northern Finland.

    Methods 

    Five hundred of the 560 (89%) eligible subjects were examined.

    The diagnosis of ARM was based on fundus photographs in 83% of the population or on ophthalmoscopic findings in 13% ; in 4%, the fundi could not be seen.

    Both early and late forms of ARM were included.

    Results 

    The prevalence of ARM increased steadily with age without overall significant difference between men and women.

    The condition was, however, related to high body mass index in men.

    The ARM appeared to be also associated with the presence of cataract, broad peripapillary atrophy, and severe sclerosis of the retinal arteries, but after controlling for age, these associations were nonsignificant.

    No association was found between ARM and systemic hypertension, diabetes, smoking, working outside, myopia, glaucoma, or the presence of exfoliation.

    In logistic regression analysis, age was the only statistically significant risk factor for ARM in both sexes.

    In men, a high body mass index also was found to be a predictor for ARM.

    Conclusions 

    The presence of ARM was associated with cataract and signs of age-related vascular changes in the eyes.

    Of the general factors, age in both sexes and high body mass index in men were found to be the only predictors of ARM.

    Mots-clés Pascal : Dégénérescence, Macula, Age, Facteur risque, Age 70-79, Vieillard, Homme, Finlande, Europe, Epidémiologie, Oeil pathologie, Rétinopathie, Maculopathie

    Mots-clés Pascal anglais : Degeneration, Macula, Age, Risk factor, Age 70-79, Elderly, Human, Finland, Europe, Epidemiology, Eye disease, Retinopathy, Maculopathy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0321985

    Code Inist : 002B09I. Création : 10/04/1997.