This report deals with clinical and immunologic studies in a butcher with work-related asthma.
Both the positive methacholine inhalation test and the significant changes observed in PEFR measurements supported the diagnosis of asthma.
The significant fall observed in PEFR measurements when the patient handled aniseed supported the diagnosis of occupational asthma.
Skin prick tests carried out with 13 spices showed positive reactions only to aniseed extract.
The patient had high levels of specific antianiseed IgE antibodies.
The bronchial challenge test with an aniseed extract showed an immediate response without a late response.
These findings suggest that the respiratory symptoms in our patient were induced by the inhalation of aniseed dust through an IgE-mediated immunologic mechanism of immediate hypersensitivity.
This study established the diagnosis of occupational asthma from aniseed dust sensitization.
Mots-clés Pascal : Asthme, Exposition professionnelle, Pimpinella anisum, Umbelliferae, Dicotyledones, Angiospermae, Spermatophyta, Allergène, Additif alimentaire, Espagne, Europe, Allergie, Etude cas, Adulte jeune, Homme, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Maladie professionnelle, Médecine travail, Immunopathologie
Mots-clés Pascal anglais : Asthma, Occupational exposure, Pimpinella anisum, Umbelliferae, Dicotyledones, Angiospermae, Spermatophyta, Allergen, Food additive, Spain, Europe, Allergy, Case study, Young adult, Human, Respiratory disease, Obstructive pulmonary disease, Occupational disease, Occupational medicine, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0320605
Code Inist : 002B06C02. Création : 10/04/1997.