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  1. Cardiovascular risk groups and mortality in an urban Swedish male population : the Malmö preventive project.

    Article - En anglais

    Objectives

    To describe the size, overlap and mortality of four cardiovascular risk groups, in order to give a scientific background for the prevention of cardiovascular disease in a representative urban population.

    Setting

    Section of Preventive Medicine, Department of Medicine, Malmö University Hospital, Malmö, Sweden.

    Subjects

    Between 1974 and 1984 22 444 men born between 1949 and 1921, constituting 75% of the total male population in these age groups, took part in a comprehensive screening examination aimed at detecting risk factors for cardiovascular disease.

    Interventions

    Those at high-risk of developing cardiovascular disease were referred to their general practitioner or to special clinics for hypertension, hyperlipidaemia and diabetes.

    The follow-up, which lasted until the end of 1991, averaged 12.2 years.

    Main outcome measures

    Total death (n=1450) and death from ischaemic heart disease (IHD) (n=471).

    Results

    Hypertension was found in 13%, hypercholesterolaemia in 19% and diabetes mellitus in 2.6% of the subjects ; 49% of the subjects smoked.

    Multiple risk factors were found in over 17% of the total cohort.

    Despite the intervention, all-cause mortality during follow-up was increased three-fold in smokers and in men with hypercholesterolaemia, four-fold in hypertensive men and five-fold in men with diabetes, compared to men with no risk factors.

    The vast majority of deaths (81%) occurred in men who smoked, had hypertension or had high serum cholesterol. (...)

    Mots-clés Pascal : Hypertension artérielle, Diabète, Hypercholestérolémie, Cardiopathie, Tabagisme, Facteur risque, Epidémiologie, Homme, Suède, Europe, Lipide, Appareil circulatoire pathologie, Endocrinopathie, Métabolisme pathologie, Hyperlipoprotéinémie

    Mots-clés Pascal anglais : Hypertension, Diabetes mellitus, Hypercholesterolemia, Heart disease, Tobacco smoking, Risk factor, Epidemiology, Human, Sweden, Europe, Lipids, Cardiovascular disease, Endocrinopathy, Metabolic diseases, Hyperlipoproteinemia

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0319656

    Code Inist : 002B30A01A2. Création : 10/04/1997.