To describe the size, overlap and mortality of four cardiovascular risk groups, in order to give a scientific background for the prevention of cardiovascular disease in a representative urban population.
Section of Preventive Medicine, Department of Medicine, Malmö University Hospital, Malmö, Sweden.
Between 1974 and 1984 22 444 men born between 1949 and 1921, constituting 75% of the total male population in these age groups, took part in a comprehensive screening examination aimed at detecting risk factors for cardiovascular disease.
Those at high-risk of developing cardiovascular disease were referred to their general practitioner or to special clinics for hypertension, hyperlipidaemia and diabetes.
The follow-up, which lasted until the end of 1991, averaged 12.2 years.
Total death (n=1450) and death from ischaemic heart disease (IHD) (n=471).
Hypertension was found in 13%, hypercholesterolaemia in 19% and diabetes mellitus in 2.6% of the subjects ; 49% of the subjects smoked.
Multiple risk factors were found in over 17% of the total cohort.
Despite the intervention, all-cause mortality during follow-up was increased three-fold in smokers and in men with hypercholesterolaemia, four-fold in hypertensive men and five-fold in men with diabetes, compared to men with no risk factors.
The vast majority of deaths (81%) occurred in men who smoked, had hypertension or had high serum cholesterol. (...)
Mots-clés Pascal : Hypertension artérielle, Diabète, Hypercholestérolémie, Cardiopathie, Tabagisme, Facteur risque, Epidémiologie, Homme, Suède, Europe, Lipide, Appareil circulatoire pathologie, Endocrinopathie, Métabolisme pathologie, Hyperlipoprotéinémie
Mots-clés Pascal anglais : Hypertension, Diabetes mellitus, Hypercholesterolemia, Heart disease, Tobacco smoking, Risk factor, Epidemiology, Human, Sweden, Europe, Lipids, Cardiovascular disease, Endocrinopathy, Metabolic diseases, Hyperlipoproteinemia
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0319656
Code Inist : 002B30A01A2. Création : 10/04/1997.