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  1. A comparison of the cost-effectiveness of sertraline versus tricyclic antidepressants in primary care.

    Article - En anglais

    There has been considerable debate concerning the cost-effectiveness of selective serotonin re-uptake inhibitors (SSRIs) versus tricyclic antidepressants (TCAs) thus far using crude prescription price comparisons or reductionist decision-analytic models.

    This paper employs a retrospective quasi-experimental design where data on service utilisation, use of medication and informal care were collected for two groups of patients in general practice settings.

    The mean cost of treatment was marginally greater for those people receiving TCA medication due to greater use of psychiatric services.

    Factors such as age, previous depression and concomitant physical illness are all associated with greater treatment costs.

    Further analysis using a prospective design is recommended.

    Mots-clés Pascal : Trouble humeur, Etat dépressif, Chimiothérapie, Traitement, Sertraline, Inhibiteur recapture, Sérotonine, Antidépresseur, Composé tricyclique, Psychotrope, Economie santé, Analyse coût, Homme

    Mots-clés Pascal anglais : Mood disorder, Depression, Chemotherapy, Treatment, Reuptake inhibitor, Serotonin, Antidepressant agent, Tricyclic compound, Psychotropic, Health economy, Cost analysis, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0318233

    Code Inist : 002B02B02. Création : 10/04/1997.