A survey of prescribing practice of antipsychotic maintenance treatment for manic-depressive outpatients.
Survey questionnaires were mailed to public hospital psychiatrists practising in a French region to obtain information on the manic-depressive outpatients they personally followed up.
Data were collected on 222 manic-depressive outpatients managed by 43 separate psychiatrists.
More than two thirds were receiving at least one antipsychotic, and 17% were prescribed a depot-neuroleptic.
Predictors of antipsychotic prescription were a history of psychotic features (OR=3.4 ; 95% CI 1.7-6.9), early age at onset (OR=2.1 ; 95% CI 1.0-4.8) and low educational level (OR=3.1 ; 95% CI 1.5-6.3).
Similar predictors were found for depot-neuroleptic prescription.
Although these indicate that the prescription of antipsychotic for manic-depressive outpatients is not random, only 14% of patients were receiving mood stabilizers only.
Owing to the potential side effects of antipsychotics, the benefit-to-risk ratio of antipsychotic use in the maintenance treatment of manic-depressive patients has to be carefully taken into account.
Mots-clés Pascal : Trouble bipolaire, Trouble humeur, Traitement, Prescription médicale, Milieu hospitalier, Neuroleptique, Psychotrope, Forme libération contrôlée, Enquête, Homme, France, Europe
Mots-clés Pascal anglais : Bipolar disorder, Mood disorder, Treatment, Medical prescription, Hospital environment, Neuroleptic, Psychotropic, Controlled release form, Inquiry, Human, France, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0318231
Code Inist : 002B02B03. Création : 10/04/1997.