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  1. Estimating the incidence of coeliac disease with capture-recapture methods within four geographic areas in Italy.

    Article - En anglais

    Study objective

    To estimate the incidence rate of newly diagnosed cases of coeliac disease in Italy.

    Design

    This was a descriptive study of coeliac disease incidence in the period 1990-91.

    Setting

    During 1990-91 newly diagnosed cases of coeliac disease were signalled by several sources including diagnostic records of departments of paediatrics, general medicine and gastroenterology, national health service records for the supply of gluten free diets and the archives of the Italian Coeliac Society.

    Patients

    Altogether 1475 cases were flagged throughout Italy, 478 ofwhom were selected, corresponding to 270 individual patients from a target population resident in four areas :

    • Provices ofTurin and Cuneo (Piedmont Region, northern Italy) ;

    • Province ofBrescia (Lombardia Region, northern Italy) ;

    • Umbria Region (central Italy) and Sardinia Region (insular Italy).

    Only for these areas were patients flagged from several sources and the reference population was identifiable.

    Main results

    The overall crude incidence rates for all ages per 100 000 residents per year were 2.4,2.7,1.5, and 1.7 in the four areas, respectively.

    The childhood cumulative incidence rates (aged ¾15 years) per 100000 live births were 143,141,72, and 80 respectively.

    The mean ages at diagnosis were similar for both childhood and adult cases throughout the areas - these were around 4 and 34 years respectively.

    For each area, the incidence rate was constantly higher in the main city than elsewhere. (...)

    Mots-clés Pascal : Coeliaque maladie, Epidémiologie, Incidence, Homme, Méthode capture recapture, Variation géographique, Italie, Europe, Appareil digestif pathologie, Intestin pathologie, Malabsorption intestinale, Immunopathologie

    Mots-clés Pascal anglais : Coeliac disease, Epidemiology, Incidence, Human, Capture recapture method, Geographical variation, Italy, Europe, Digestive diseases, Intestinal disease, Intestinal malabsorption, Immunopathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0317967

    Code Inist : 002B13B03. Création : 10/04/1997.